{"id":16974,"date":"2024-11-12T19:14:20","date_gmt":"2024-11-12T18:14:20","guid":{"rendered":"https:\/\/francelyme.fr\/site\/?p=16974"},"modified":"2024-11-12T19:14:21","modified_gmt":"2024-11-12T18:14:21","slug":"20-millions-de-dollars-pour-etudier-les-causes-de-la-forme-chronique-de-lyme","status":"publish","type":"post","link":"https:\/\/francelyme.fr\/site\/20-millions-de-dollars-pour-etudier-les-causes-de-la-forme-chronique-de-lyme\/","title":{"rendered":"20 millions de dollars pour \u00e9tudier les causes de la forme chronique de Lyme"},"content":{"rendered":"
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Aux USA, les chercheurs de l\u2019Universit\u00e9 Tufts viennent de recevoir une subvention de 20,7 millions de dollars des National Institutes of Health (NIH, \u00e9quivalent de l\u2019INSERM en France, en 30 fois plus gros) pour mener une \u00e9tude approfondie sur la forme chronique de la maladie de Lyme. Ce projet, la plus grande \u00e9tude prospective financ\u00e9e par le NIH \u00e0 ce jour, vise \u00e0 comprendre pourquoi certains patients d\u00e9veloppent des sympt\u00f4mes persistants apr\u00e8s leur traitement initial.<\/p>\n\n\n\n

Car m\u00eame lorsque la maladie est bien diagnostiqu\u00e9e et trait\u00e9e tr\u00e8s t\u00f4t, la recherche a prouv\u00e9 que 14% des patients en moyenne vont d\u00e9velopper des sympt\u00f4mes chroniques. Cela n\u2019est plus discut\u00e9 par personne \u00e0 pr\u00e9sent. A ces patients, il faut bien s\u00fbr ajouter tous les malades qui n\u2019ont pas \u00e9t\u00e9 diagnostiqu\u00e9s au d\u00e9part, voire qui ne le sont toujours pas, et ceux qui n\u2019ont pas re\u00e7u le traitement standard au stade initial (2 \u00e0 3 semaines d\u2019antibiotique), et dont beaucoup malheureusement d\u00e9veloppent aussi la forme chronique.<\/p>\n\n\n\n

Comme nous le savons bien, ces patients souffrent de sympt\u00f4mes persistants comme la fatigue, des douleurs musculaires, articulaires, des troubles neurologiques, et aussi de beaucoup d\u2019autres sympt\u00f4mes invalidants, variables selon les personnes, pendant des mois ou des ann\u00e9es.<\/p>\n\n\n\n

Pour les chercheurs de Tufts, la situation est la suivante : \u00ab Il n’y a pas d’accord sur les m\u00e9canismes \u00e0 l’origine de la maladie ou sur la fr\u00e9quence \u00e0 laquelle elle se produit. Il est m\u00eame difficile de calculer le nombre de cas. Car les sympt\u00f4mes tels que la fatigue, les douleurs musculaires et les troubles cognitifs sont similaires \u00e0 ceux signal\u00e9s pour d’autres maladies, y compris la grippe, la fibromyalgie, le syndrome de fatigue chronique et le COVID long \u00bb.<\/em><\/p>\n\n\n\n

Pour tenter de comprendre pourquoi certains gu\u00e9rissent compl\u00e8tement tandis que d\u2019autres souffrent de sympt\u00f4mes prolong\u00e9s, l\u2019\u00e9quipe de recherche a d\u00e9cid\u00e9 de suivre 1000 patients atteints de Lyme aigu\u00eb (phase initiale de la maladie). L\u2019id\u00e9e est d\u2019\u00e9tudier sur une longue p\u00e9riode l\u2019\u00e9volution de tous les param\u00e8tres et marqueurs biologiques pertinents, en regard des sympt\u00f4mes pr\u00e9sent\u00e9s par les patients.<\/p>\n\n\n\n

Avec de tels moyens, le Dr Linden Hu et son \u00e9quipe pluridisciplinaire esp\u00e8rent que ces travaux permettront de mieux diagnostiquer, pr\u00e9venir et traiter cette maladie.<\/p>\n\n\n\n

Pour en savoir plus :<\/p>\n\n\n\n

https:\/\/www.lymedisease.org\/tufts-studying-chronic-lyme<\/a><\/p>\n\n\n\n

https:\/\/now.tufts.edu\/2024\/09\/17\/large-scale-study-will-seek-unearth-causes-persistent-symptoms-lyme-disease<\/a><\/p>\n\n\n\n

https:\/\/www.youtube.com\/channel\/UCdpCZA0rU085ke9fNuAo-Fg<\/a><\/p>\n\n\n\n

https:\/\/tuftslymedisease.org<\/a><\/p>\n\n\n

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